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Back Issues  —  2000

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2000 NEWS ARTICLES
2000, some ups, some downs and some wishes for 2001 December 2000: Despite some negative publicity about vaccines, vaccination of America's children is at a record high.
AAP releases recommendations for Lyme vaccine February 2000: Vaccination should be based on risk assessments for high-risk individuals older than 15.
AAP updates recommendations for routine use of varicella vaccine February 2000: Pediatricians urged to support public health officials in development and implementation of immunization requirements for child care and school entry.
ACIP modifies meningitis vaccination recommendation for college students January 2000: Vaccination should be provided or made easily available to college freshmen who wish to reduce their risk.
ACIP recommends routine use of pneumococcal vaccine for infants March 2000: The vaccine series should be given in four doses at 2, 4, 6 and 12 to 15 months of age.
All pregnant women need HIV testing, regardless of apparent risk July 2000: HIV testing should be as commonplace as urinalysis during a woman's first prenatal office visit.
Amoxicillin/clavulanate superior to azithromycin for AOM, study finds March 2000: The drug was shown to be more effective at both killing the bacteria and reducing symptoms.
Antibiotic management challenging for meningitis in pediatric patients October 2000: For pneumococcal meningitis, vancomycin is considered standard initial treatment before knowing the susceptibility of the organism.
Antibiotic treatment for E. coli O157:H7 increases risk for HUS July 2000: Study shows 50% of the children who received antibiotics for E. coli infection developed hemolytic-uremic syndrome.
Asthma may result from early immune responses that alter lung growth February 2000: Prevention of asthma must be initiated in early life since developmental changes in the lungs begin shortly after birth.
Athletes with HIV, HBV and HCV should be permitted to participate in sports January 2000: AAP releases new policy statement that says exposure to blood poses small risk.
Bacterial meningitis outcome may be predictable within 12 hours of admission November 2000: Long seizure duration, presence of coma, leukopenia and use of inotropes all point to adverse outcomes.
Better follow-up needed for infants born with sickle cell disease November 2000: Large discrepancies in compliance seen with medical interventions for infants with sickle cell disease.
Birth dose of hepatitis B vaccine slow to recover after thimerosal scare May 2000: A delay in the receipt of the first dose of hepatitis B vaccine is directly correlated with delayed completion or noncompletion of vaccine series.
Breaching the comfort zone: talking about sex September 2000
CDC Lyme disease surveillance shows incidence on the rise June 2000: The number of counties that reported Lyme disease did not increase, suggesting a good portion of the rise came from areas already known to be Lyme-endemic.
CDC project trying to track unexplained, life-threatening illnesses December 2000: A researcher said the number of cases with no etiology, even after extensive testing, is astonishing.
Cases of Shiga toxin-producing E. coli reported in United States February 2000: A study confirms that Shiga toxin-producing E. coli O111:H8 is capable of causing infection in healthy individuals.
Changing standard of care important in managing inner-city asthma June 2000: A focused care approach may reduce the number of acute care visits to emergency departments and clinics.
Child care center staffs contribute to inappropriate antibiotic prescribing May 2000: Child care workers seem to be misinformed about several aspects of upper respiratory infections and antibiotic use.
Children may not be getting enough liquid medicine to finish course September 2000: Antibiotic suspensions as dispensed may not be enough to complete dosing regimens.
Children unvaccinated due to beliefs at greater risk for contracting measles January 2000: Religious and philosophical exemptions pose potential risk to community.
Clues offered in diagnosing a child with fever of unknown origin May 2000: Consider toxicity, immune status, fever duration, age, infection source and severity of infection.
Combination therapy offers better treatment option December 2000: Combination medications for asthma can simplify dosing. They also offer improved effectiveness and better compliance.
Consider many factors when determining the cause of otorrhea August 2000: Otorrhea is a common complication of tympanostomy tube placement, but it has several other causes.
Consider resistant pathogens when prescribing for acute conjunctivitis October 2000: H. influenzae is still the most prevalent cause. However, when S. pneumoniae is the cause, almost one-third of cases are resistant.
Corticosteroids should not be used for treating infant RSV February 2000: Treatment with prednisolone had no effect on outcome measures at initial hospital admission for RSV infection.
DNA markers effective as surrogate indicators of NICU pathogen transmission May 2000: DNA markers from the cauliflower mosaic virus were effective in detecting pathways of nosocomial pathogen transmission in a given NICU environment.
Day care children saw reduction in RTIs after nine-valent pneumococcal vaccine June 2000: A nine-valent pneumococcal vaccine affected morbidity and antibiotic use in the day care setting.
Determining impact of new pneumococcal conjugate vaccine December 2000: A new indication for otitis media was filed with the Food and Drug Administration.
Diagnosis, treatment of bacterial sinusitis clarified in guidelines August 2000: The new guidelines recommend antibiotics for children with symptoms persisting longer than 10 days without improvement.
Dutch pertussis outbreak may have been caused by antigenic changes October 2000: Pertussis has remained endemic in the Netherlands with epidemic peaks, despite high vaccination coverage.
E. coli outbreak involving 18 school children reported in Minnesota May 2000: The USDA's Food and Nutrition Service plans to destroy all meat from the implicated lot.
Early predictors could improve immunization status August 2000: Social cognitive variables assessed at 3 months were predictive of immunization status and could be targeted for later interventions to prevent delays.
FDA approved new treatment for acute otitis media February 2000: Trimethoprim alone appears to be efficacious in treatment of acute otitis media.
FDA approves fluticasone powder for asthmatics older than 4 years November 2000: Because there is no need for hand-breath coordination, this new style inhaler may be easier to use than traditional aerosol inhalers.
FDA approves pneumococcal conjugate vaccine for use in infants March 2000: The vaccine should be routinely administered to infants at 2, 4, 6 and 12-15 months of age.
Features of exanthems helpful in diagnosing childhood disease May 2000: Kawasaki syndrome, fifth disease and Gianotti Crosti syndrome are diseases associated with exanthems.
Gene alterations for CF may account for chronic sinus problems November 2000: Many patients who suffer from chronic sinusitis share an altered gene, which is present in CF patients.
Group A streptococcal perineal disease is relatively common November 2000: Coinfection with streptococcal pharyngitis is common. Young age and school attendance may be risk factors.
Guidelines preventing some, but not all early-onset group B streptococcus August 2000: GBS cases have decreased 65% since 1993, and the gap between blacks and whites has narrowed by 75%.
Health care workers on frontline facing unending challenges August 2000: The newest challenges include an often complacent or self-diagnosing public.
Heart failure deaths common in pediatric HIV; HF often misdiagnosed November 2000: Regular echocardiograms in children with HIV may help alter the course, stem suffering.
Hepatitis B virus eradication easier than smallpox, polio June 2000
Herpesvirus infections most deadly in first four weeks of life June 2000: Forty percent to 90% of Americans have HSV-1; 15% to 30% have HSV-2.
Highest ever coverage reported for DTP, HepB and varicella vaccines November 2000: ACIP approves recommended childhood immunization schedule for January through December 2001.
Household contacts of confirmed GAS cases at risk for disease October 2000: The overall annual incidence of invasive GAS disease is 3.8 cases per 100,000 population.
Hypertrophic pyloric stenosis reported after erythromycin January 2000: Prophylaxis for exposure to pertussis still important as most hospitalizations and deaths for pertussis occur in infants.
IOM report says immunization system not prepared to meet future needs July 2000: A new financial strategy is aimed at bolstering immunization system infrastructure.
IOM report says medical errors are a 'systemwide' problem January 2000: Managed care escapes harsh criticism, but new practice requirements for medical professionals could be coming.
Immunologic correlates useful predictor of vaccine protection July 2000: Shorter prelicensure periods and decreased costs associated with developing new vaccines are benefits of using correlates of protection.
Increase in Hib disease prompts CDC to investigate Amish population April 2000: While Hib vaccine is recommended for all children younger than 5 years, many Pennsylvania children remain unvaccinated.
Influenza season started early and spread rapidly across country February 2000: While people of all ages are affected, the very young are particularly hit hard.
Inhaled corticosteroid use associated with misconceptions May 2000: Many myths exist among clinicians and patients about safety and optimal benefits of inhaled corticosteroids.
Intranasal spray vaccine protects against unexpected influenza strain March 2000: The first-year study results showed an efficacy rate of 93% and the second year of this study suggested similar results.
Intranasal steroids most effective treatment for allergic rhinitis December 2000: More physicians are recognizing the benefit of first-line use of intranasal steroids.
Is your patient really allergic to that antibiotic? December 2000: Find out what type of reaction the patient had when he or she claims to be allergic to antibiotics.
Kawasaki syndrome not caused by Chlamydia pneumoniae April 2000: However, an infectious etiology is still a leading hypothesis about the cause of this problem.
Lack of funding forcing closure of school-based health centers September 2000: School-based health centers are often the students' sole source for health care. Closing the centers leaves many students without access to a health care provider.
Lactobacillus GG with antibiotics reduces antibiotic-associated diarrhea January 2000: Probiotic strain Lactobacillus GG shown safe and effective in prevention of diarrhea in children receiving antimicrobial treatment.
Laws needed for hepatitis B vaccination compliance April 2000: A survey has found that in the absence of school entry requirements, many do not receive HepB.
Lice remains hard-to-treat common disease among children April 2000: There may be several treatment options available, but none is 100% effective.
Lidocaine-prilocaine patch does not affect antibody response to MMR October 2000: Patch reduces pain associated with vaccination and causes no diminution in antibody response to vaccine.
Linezolid is well tolerated in children with CAP June 2000: At follow-up, 92% of study patients on linezolid were considered cured, including six patients with pneumococcal infections.
Lyme disease vaccine as effective in children as in adults May 2000: A study of more than 4,000 U.S. children showed the safety profile of Lyme disease vaccine is similar to that in adults.
Management of allergic rhinitis should consist of three-part system April 2000: Symptom management should be approached with avoidance, pharmacologic therapy and allergen immunotherapy.
Many issues to consider when initiating systemic steroid therapy July 2000: Clinicians should advise parents on issues including weight gain and behavioral changes while their child is on steroid therapy for a dermatologic condition.
Meningococcal vaccine guidelines for students published August 2000: The CDC is encouraging college students, particularly freshmen living in dormitories, to be vaccinated.
Neonatal dermatology presents unique problems May 2000: Premature skin needs special precautions. Consider biopsy and maternal history when making diagnosis.
Neuraminidase inhibitors effective for treating flu December 2000: Studies have shown that they are effective against both influenza A and B, and they have demonstrated better ability to reduce complications.
Nevirapine reduces HIV vertical transmission after one year August 2000: At a 12-month follow-up, a 39% reduction in maternal-child HIV transmission was noted.
New 3-D structure allows look into poliovirus as it enters a host cell March 2000: By understanding the process of how viruses work, researchers have another target for intervention.
New and old options exist for the management of acute otitis media November 2000: Vaccines, antibiotics, tympanocentesis/myringotomy, tympanostomy tubes and adenoidectomy are available therapeutic options for the child with recurrent disease.
New data indicate U.S. RSV season in full swing January 2000: The winter months mean peak time for respiratory syncytial virus.
New guidelines specify when to use antimicrobials for rhinosinusitis September 2000: Beginning with a broad-spectrum drug may have a better chance of success, but limits options if it does not work.
New online HIV treatment guidelines for adolescents, adults available March 2000: Recommendations for the use of resistance tests are now included.
No link found between Stachybotrys and pulmonary hemorrhage in infants April 2000: Hemorrhage was associated with major water damage during the six months before illness and increased levels of measurable household fungi.
Number of polio-endemic countries decreasing July 2000: New data indicate polio remains endemic in only 30 countries worldwide, a decrease from 50 in 1998.
Ocular allergy symptoms can have many allergic, nonallergic causes August 2000: Each cause has different clinical signs. Some nonallergic diseases can mimic allergic reactions.
Offer parents option to have young children immunized against influenza March 2000: Feasibility issues make it complicated to give young children influenza vaccine, but children younger than 1 year have the same hospitalization risks as the elderly.
Ohio reports cluster of GAS cases April 2000: Seven patients developed streptococcal toxic shock syndrome and two died.
Pacifier use may increase the risk of acute otitis media October 2000: AOM occurrence was 29% lower among children whose parents were counseled against pacifier use.
Parents need to be advised on safety of combination vaccines May 2000: Although evidence proves that combination products are safe and effective, some parents still need convincing.
Pediatric, neonatal intensive care units at risk for nosocomial infections July 2000: Bloodstream infections were found to be the most common; invasive devices found to play a major role.
Pediatricians are still wary about fluoroquinolone use in children December 2000: Indications for upper respiratory infections like acute otitis media could lead to increased resistance.
Pediatricians ask about the pneumococcal vaccine April 2000
Permission, instruction needed to have asthma meds in school February 2000: Although policy differs from district to district, most schools allow students to self-carry, self-medicate.
Pneumocystis carinii and SIDS: possible link or marker for syndrome? March 2000: Up to 94% of immunocompetent children have detectable antibodies by age 30 months to 48 months.
Preventing perinatal infections: lessons learned from two successes October 2000: Recommendations to prevent HIV and group B streptococcus helped lower the number of cases of maternal-fetal transmissions.
Pseudomonas aeruginosa under nails of HCWs spreads infection April 2000: The genotypes found under the fingernails of three nurses matched cultures from infected neonates.
Quinupristin/dalfopristin benefit shown in pediatric patients March 2000: The overall treatment success rate was 71%. A 51.1% success rate was reported in the adult population.
Revisiting treatment, management of tinea capitis June 2000: Diagnostic techniques and treatment options have greatly changed.
Routine ENT follow-up visits for tympanostomy tubes: Are they necessary? September 2000: Several important questions must be answered at follow-up visit after tympanostomy tube placement. It is important for pediatricians to work with the surgeons.
Severe local, systemic reactions can result from fire ant stings June 2000: Patients given the imported fire ant whole-body vaccine can become tolerant or desensitized to the protein in fire ant venom.
Signs, symptoms may vary among strains of influenza October 2000: Influenza is responsible for 15% to 30% of excess winter hospitalizations for respiratory illness.
Simple tools and techniques make asthma management easier July 2000: Simple tools, such as surveys, give doctors more time to teach patients how to better manage their illness.
Some risky behaviors are declining among teens, but not all September 2000: More teens are protecting themselves against HIV and pregnancy. However, many are still taking other risks, such as drinking and taking illegal drugs.
Statistics show substantial decline for neonatal group B strep February 2000: Prophylactic intrapartum antibiotics prevented approximately 3,900 early-onset infections and 200 neonatal deaths in 1998.
Study proposes easy method of telling whether patients are compliant September 2000: Simply calling a pharmacist may help pediatricians determine compliance.
Therapy advances improve asthma management September 2000: Two new asthma therapies treat mechanistic aspects of the disease by attempting to limit the allergic response that causes asthma.
Therapy, education key to asthma management in preschoolers March 2000: Early recognition of asthma plus appropriate drug therapy and education are key to disease management.
Timing of fevers is important for diagnosing recurrent fevers December 2000: Fixed vs. irregular fever interval is important for the differential diagnosis.
Treating meningitis still an issue for pediatricians October 2000: Although Hib is not a large culprit these days, S. pneumoniae and N. meningitidis meningitidis meningitis are.
Treatment guidelines for antibiotic use in bacterial sinusitis November 2000: Because of its commonality and the increasing prevalence of bacterial resistance to antibiotics, the appropriate use of antibiotics in treating sinusitis has recently been addressed.
Unvaccinated Minnesota teen dies from chickenpox January 2000: Vaccination prior to contracting the disease or treatment with acyclovir might have saved his life.
A urine culture is still needed to rule out UTI September 2000: Dipstick analysis missed 30% of culture-positive cases, and standard microscopy did little to improve this.
Varicella vaccine eliminates disease incidence among day care attendees February 2000: Study shows 134 cases of varicella occurred among unvaccinated children vs. 11 cases in vaccinated children in day care setting.
Varicella vaccine safety: The report card November 2000: Reactions related to the varicella vaccine need to be reported to keep physicians alert.
What to do when religion is a barrier to treatment November 2000: Have a procedure in place to deal with religious barriers to necessary treatment before decisions must be made.
What's Your Diagnosis? A monthly case study, with treatment information and discussion to follow.
Zinc supplements, reduced disease related in developing countries January 2000: Zinc reduces pneumonia by 41% and diarrhea by up to 25% in children younger than 5 years old.




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