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Back Issues — 2001 |
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The following is a list of online articles appearing in Infectious Diseases in Children. Hyperlinks for the online articles are provided below. If you would like an article that is not available online, please contact SLACK Incorporated Customer Service at (800) 257-8290 or (856) 848-1000, ext. 281 or 237. To subscribe to the printed newspaper, delivered monthly, you may call SLACK Incorporated Customer Service or use our online form. |
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| ASTHMA, ALLERGY AND IMMUNOLOGY | |
|---|---|
| Diagnosing childhood asthma involves several overlapping factors | June 2001: From statistics to genetics, all ongoing research points to no definitive way to test. |
| FDA panel agrees certain allergy drugs would be safe as OTC products | June 2001: The FDA faces many legal and regulatory hurdles if it is to make the drugs available without a prescription. |
| Knowledge of immunodeficiencies now applicable to other diseases | March 2001: Clinical lessons in cell function and antibody response from the watershed of immunology. |
| Medication and environmental controls can manage pediatric asthma | August 2001: Controlling the environment can lessen the need for medication use. |
| Montelukast effective in controlling asthma in preschoolers, study finds | October 2001: Administered as a 4-mg chewable tablet, it produced “significant improvements” compared with placebo. |
| New bronchodilator approved for maintenance treatment of asthma | March 2001: Formoterol fumarate inhalation powder is not indicated for patients whose asthma can be managed by occasional use of inhaled, short-acting ß2-agonists. |
| Patient observation required for test dosing with penicillin allergy | March 2001: After 10 years, study showed 30% of children with a penicillin-allergic reaction still had IgE antibodies. |
| Patients may be allergic to food additives in medicines, not the drug | February 2001: Rather than the drug itself, patients may be allergic to flavorings or colorings. |
| Urban, minority, low-income children face many barriers to good asthma care | February 2001: Parental health beliefs should be considered when treating inner city children with asthma. |
| BREAKING NEWS AND COMMENTARY | |
|---|---|
| AAP releases complementary and alternative medicine policy | May 2001: Pediatricians should provide balanced advice, guard against bias and maintain a trusting relationship with parents. |
| Bioterrorism terrorizes the U.S. | December 2001: Following the World Trade Center attacks, Americans then experienced biological attacks. |
| Bioterrorism threat seems very real | October 2001: Anthrax, plague, Ebola and other viruses are all recognized threats. |
| Ear drops may reduce pain of AOM and allow spontaneous resolution | May 2001: Parents may accept this alternative to antibiotics, although study was small. |
| Erythromycin and infantile hypertrophic pyloric stenosis linked | November 2001 |
| FDA looks favorably upon new version of amoxicillin/clavulanate | February 2001: An FDA panel recommended the use of Augmentin ES as empiric therapy in a selected high-risk population. |
| FDA panel favors azithromycin short-course for AOM treatment | December 2001: The new indication could make compliance easier and more children may complete their antibiotic course. |
| Is there a connection between MMR vaccination and onset of autism? | April 2001: Most experts say no. Some physicians and parents disagree. The IOM, CDC and other agencies are looking for answers. |
| Law on pediatric drug testing facing renewal | June 2001: Successful FDA incentive for companies to study drugs in children might be renewed by Congress for 5 years. |
| Number of confirmed anthrax cases keeps rising | November 2001 |
| Ohio reports three meningitis cases, vaccinates more than 4,000 | July 2001: Some may suggest that the Ohio Department of Health was more aggressive than necessary. |
| Pneumococcal conjugate vaccine temporarily delayed | October 2001: Temporary deferment of low-risk patients for pneumococcal conjugate vaccine is suggested. |
| Shortage of tetanus, diphtheria toxoid-containing vaccines possible | March 2001: Sporadic supply, decreasing market share and the loss of two manufacturers jeopardize vaccine supply. |
| EMERGING DISEASES | |
|---|---|
| Atypical Kawasaki disease may go unrecognized, lead to coronary disease | September 2001: Diagnosis can be difficult, because signs and symptoms may be subtle. |
| Chronic Lyme disease not helped by antibiotics | September 2001: None of the samples showed evidence of persistent infection with Borrelia burgdorferi. |
| Dominican Republic, Haiti hit by polio outbreak linked to OPV strain | December 2001: The Western Hemisphere had been free of wild poliovirus since 1991. |
| IV acyclovir recommended in high doses for neonatal herpes virus | October 2001: Study probes the safety of high-dose acyclovir in the management and treatment of neonatal herpes simplex virus infections. |
| New Haemophilus influenzae pathogen may be emerging | October 2001: Some have speculated that non-b serotypes of Haemophilus influenzae may replace Hib as a serious pathogen. |
| GASTROINTESTINAL | |
|---|---|
| Although many do not realize, hepatitis is a pediatric disease | July 2001: Children are at-risk for hepatitis A, B and C, and pediatricians must be prepared to prevent these infections. |
| HIV/AIDS & STDs | |
|---|---|
| Mother-to-child HIV transmission decreasing in developed countries | March 2001: Reducing mother-to-child HIV transmission in less developed parts of the world will require much more than just peripartum treatment. |
| Nevirapine taken after occupational HIV exposure shown to cause toxicity | February 2001: The CDC reported two cases of life-threatening hepatotoxicity and 22 other cases of adverse events in health care workers taking nevirapine after exposure. |
| Seropositivity of one CMV strain does not protect women from all strains | July 2001: This means that their newborns may not be protected against congenital cytomegalovirus. |
| INFECTIONS OF THE SKIN | |
|---|---|
| Anaerobes found in infected piercing sites | August 2001: This may be the first report of anaerobic bacteria causing infections in body piercings. |
| Clinical presentation of many lesions overlap | April 2001: It is important to look for subtle differences in the differential diagnosis. |
| Periodic topical shampoo may be best treatment for tinea versicolor | May 2001: Tinea gladiatorum is on the rise due to the increased popularity of wrestling among children. |
| T. capitis, other fungal infections may be managed with prophylaxis | July 2001: While fungal infections can be effectively treated with oral and topical drugs, prophylaxis is also useful in some types of infection control. |
| Treating lice, nits and other bad bugs | September 2001: School policies requiring exclusion from school and treatment for all children with nits alone are probably excessive. |
| ISSUES IN OTITIS AND SINUSITIS | |
|---|---|
| Otorrhea: need to get medication past debris | November 2001 |
| Uncomplicated sinusitis: a literature review | November 2001: Limited data show that antibiotic treatment for uncomplicated sinusitis of any etiology is effective. |
| ‘Watchful waiting’ may be good first choice for treating AOM | November 2001: Most uncomplicated cases of AOM resolve spontaneously without apparent suppurative complications. |
| NEWS OF GENERAL PEDIATRICS | ||
|---|---|---|
| AAP, APS issue guidelines for managing pain in children | October 2001: Despite barriers to treatment, pediatricians should focus on recognizing and treating pain for all children. | |
| AAP releases new clinical practice guidelines for treatment of ADHD | November 2001: Ongoing communication with parents, teachers and other school professionals is necessary to monitor the progress and effectiveness of specific interventions. | |
| Beautiful creatures can entice children, but their ‘bite’ is bad | May 2001: Jellyfish stings, coral cuts and puncture wounds are a few of the injuries that can occur when kids encounter dangerous marine animals. | |
| NOSOCOMIAL INFECTIONS | |
|---|---|
| Keyboards implicated as reservoirs of nosocomial pathogens in ICUs | May 2001: A swab moved over a computer keyboard found multi-resistant Staphylococcus aureus, Enterococcus, Enterobacter and other gram-negative rods. |
| NICU equipment, devices partly to blame for high infection rates | July 2001: Improving hand-washing compliance, protecting neonate skin and limiting visitors may all have an impact, but none of these is easy to accomplish. |
| Periodic topical shampoo may be best treatment for tinea versicolor | May 2001: Tinea gladiatorum is on the rise due to the increased popularity of wrestling among children. |
| RESIDENT ROUNDS | |
|---|---|
| E. coli O157:H7 in a teenage mother and her newborn infant | August 2001: The goal of Resident Rounds is to share with our readers the wealth of clinical experience gained every month by pediatric residents and infectious disease fellows. |
| RESPIRATORY INFECTIONS | |
|---|---|
| AAP provides guidance on diagnosing and treating sinusitis | October 2001: The proper antibiotic course can usually resolve bacterial sinusitis before severe or fatal complications occur. |
| AAP releases guidelines for sinusitis treatment | December 2001: Guidelines call for proper diagnosis, appropriate use of radiographs and judicious antibiotic use. |
| About 4 million children worldwide die each year from respiratory illness | October 2001: Large inequities in access to care almost guarantee their deaths. |
| Consider otorrhea when deciding duration of tube insertion | August 2001: Purulent discharge appeared more frequently in children with extended tympanostomy tube placement. |
| Consider RSV in all patients during the winter months | January 2001: Surveillance data from the 1999-2000 season show widespread activity occurred from late October 1999 through late March 2000. |
| Dexamethasone may pose a risk of intestinal perforation in preemies | April 2001: Early postnatal doses of dexamethasone are not indicated to prevent lung disease in extremely low birth weight infants. |
| High-dose amoxicillin-clavulanate may fill an important niche | March 2001: Clinical trial data presented to the FDA show the formulation eradicated 98% of S. pneumoniae, including 93% of PRSP. |
| Influenza vaccine: shortages still likely, but there will be more vaccine than last year | September 2001: The CDC said to expect delays again this year, so vaccinate high-risk individuals first. |
| Managing young febrile infants with otitis media | June 2001: Office practitioners managed the children successfully without extensive tests or hospitalization. |
| Many approaches exist to diagnose and to treat respiratory infections | January 2001: Putting together the right information from history, exam and the laboratory can help determine the best diagnosis and treatment. |
| Oseltamivir approved for influenza prophylaxis | January 2001: Although oseltamivir shows efficacy in flu prevention, vaccination should remain first-line defense. |
| Protecting kids against influenza begins with maternal immunization | September 2001: The vaccine can’t be given to babies younger than 6 months, so this is the only way to protect these infants. |
| Whether otitis media will develop depends on many different factors | March 2001: Recurrent otitis media has many contributing factors, such as day care attendance and genetics. |
| TRAVEL MEDICINE | |
|---|---|
| Dominican Republic hit by polio outbreak linked to OPV strain | January 2001: The Western Hemisphere had been free of wild poliovirus since 1991. |
| Epidemiologists working toward global elimination of measles | February 2001: Three of the six regions of the World Health Organization have announced goals to eliminate measles. |
| VACCINE-PREVENTABLE DISEASES | |
|---|---|
| ACIP updates vaccination guidelines for children adopted from overseas | January 2001: Vaccination certificates may not necessarily equate with protection against diphtheria and tetanus. |
| Biken DTaP found to be safe, effective for fifth dose | December 2001: The vaccine induced more local reactions after the fifth dose than the fourth dose, but fewer systemic ones. |
| CDC calls for conservation of tetanus vaccine supply | July 2001: The tetanus toxoid shortage has led the CDC to recommend delaying routine booster shots until 2002. |
| College freshmen in dorms at slightly greater risk for meningitis | September 2001: TM casts, intramembraneous cholesteatoma, tympanosclerosis, implantation cholesteatoma, tympanic membrane retraction pockets and cholesterol granuloma are discussed. |
| Committee votes against recommending approval of Infanrix combination vaccine | April 2001: Committee members felt there wasn't enough data concerning safety and efficacy of the combination vaccine in U.S. children. |
| Congenital rubella syndrome occurs among infants of foreign-born women | May 2001: The rate of confirmed and probable CRS among infants in this mostly Hispanic population is higher than the reported U.S. rate since introduction of the vaccine. |
| FDA panel does not recommend approval of FluMist | August 2001: An FDA advisory committee wants more analysis of data before recommending licensure. |
| FDA panel requests more safety data, surveillance for LYMErix | March 2001: Advisory committee member says accelerated post-marketing data need to prove there are no new safety concerns regarding the vaccine. |
| Influenza vaccinations in children reduce disease spread within family | January 2001: Unvaccinated household members of vaccinated children had 42% less febrile respiratory illness. |
| IOM report: No link found between MMR vaccine and autism | May 2001: The committee did not recommend a policy review of the licensure of MMR vaccine. |
| IPV vs. OPV: no difference in immunization rates nationwide | August 2001: An IPV-containing schedule does not adversely affect immunization rates when compared with the all OPV schedule. |
| Latest figures indicate incidence of Lyme disease may be increasing | April 2001: Different scenarios may have contributed to reported cases of the disease. |
| Lyme disease vaccine well tolerated, immunogenic in children | August 2001: Lyme disease is the most common vector-borne disease in the United States. |
| Middle school vaccination requirements can help raise rates | September 2001: Cooperation by the public health community is necessary to achieve a high level of coverage. |
| New pneumococcal vaccine effective against nasopharyngeal carriage | June 2001: Although vaccinated children were less likely to carry a vaccine strain of S. pneumoniae, they were more likely to carry a non-vaccine strain. |
| No link found between thimerosal, neurodevelopmental disorders | November 2001: Data were extremely limited regarding the possible link, but vaccines provide a known benefit. |
| Parents can participate in study of child health | December 2001 |
| Prevnar shortage may disrupt childhood vaccination schedule | December 2001: The American Academy of Pediatrics is considering a recommendation to eliminate 1 dose from the series. |
| Selective immunization with HepA has minimal impact on population | January 2001: Half of the reported cases of hepatitis A occur in people with no known risk factors. |
| Strategy for preventing measles outbreaks appears to be working | July 2001: The incidence of measles in the United States is less than 1 per million; most cases are imported. |
| Top story for 2001: no link found between MMR vaccine and autism | December 2001: The IOM issued two reports this year about the safety of vaccines. |
| Varicella incidence has decreased | July 2001: National vaccine coverage is at more than 63%, with state and urban areas ranging from 28% to 82%. |
| Volunteers needed for polio eradication effort | November 2001: STOP teams work toward strengthening surveillance and vaccination efforts in polio eradication program. |
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